GTA VI marks a major shift in how Rockstar tells its stories. Instead of GTA V's three-character system, the game focuses entirely on Jason and Lucia — a deliberate choice to deliver a more emotionally driven, cohesive narrative closer to Red Dead Redemption 2 than the sprawling satire of GTA V.

Players can switch between both characters during free roam and missions, with different outcomes and voice lines depending on who you control. Their relationship evolves from a criminal partnership into something deeper — with Rockstar suggesting their dynamic is central to the entire story.

The game is set against the backdrop of modern-day Vice City and the state of Leonida — a satirical take on 2020s Florida, complete with social media culture, influencer chaos, and a criminal underworld that stretches far beyond the city limits.